Northern Territory Police are investigating a fatal crash that occurred in Wickham Point overnight.

Just before 5am, the Joint Emergency Services Communications Centre received a report of a single vehicle rollover on Channel Island Road.

Police and St John Ambulance responded to the scene, where they found a deceased female, aged 29, inside the vehicle. She was the sole occupant.

Major Crash Detectives have arrived at the scene and are currently investigating. A crime scene has been established, and one lane of the road is open, although traffic delays are likely.

The time and circumstances surrounding the crash remain under examination.

The number of lives lost on NT roads this year has reached 51, compared to 21 at the same time last year.