The Northern Territory Police Force is investigating following a fatal crash that occurred in the Katherine Region yesterday afternoon.

Around 4:50pm, the Joint Emergency Services Communication Centre received reports of a collision between a road train and a Honda CRV, approximately 14km north of Katherine on the Stuart Highway.

Emergency services attended the scene and the sole occupant of the Honda, a 23-year-old male, was pronounced deceased at the scene.

The 58-year-old driver of the road train was assessed for minor injuries and later conveyed to Katherine Hospital for blood testing.

A crime scene was established, and investigations remain on going.

Detectives from Major Crash Investigation Unit urge anyone with information about the incident or who may have dash-cam footage to make contact on 131 444. Please quote reference number P25200551.

The lives lost on Territory roads now stands at 24.