Major Crash investigators are calling for information on a road crash involving a bus and a cyclist in Darwin City on Monday morning.

The bus was turning left onto Cavenagh St from Daly St when the collision occurred about 7am. The 25-year-old male suffered serious leg injuries in the crash.

Investigators are urging anyone who witnessed the crash or the cyclist in the moments before the crash, or who may have dashcam footage, to contact police on 131 444 or Crime Stoppers on 1800 333 000.