Major Crash Detectives are investigating the circumstances surrounding a crash that led to the death of a female overnight.

Acting Superintendent Serge Bouma said police attended a single vehicle crash that occurred around 8.20pm on the Roper Highway.

“There were six people in the vehicle, a female, yet to be identified, died at the scene. Four others were conveyed to Katherine Hospital for treatment,” he said.

“A 48-year-old male was arrested and is currently assisting police with further enquiries,”

Investigations are ongoing, however, police believe alcohol may be a contributing factor.

The Territory road toll now stands at 33 compared with 37 at the same time last year.