Northern Territory Police are seeking public assistance following an assault on a man in Alice Springs on Wednesday night.

A man was walking north on Todd Street towards the Todd Mall when he was approached by a group of young people asking for cigarettes, just after midnight.

The man refused them and continued walking along Gregory Terrace when it is alleged he was set upon by two members of group who knocked him to the ground and continued to assault him.

The man received significant lacerations to the head and jaw and was transported to the Alice Springs Hospital for treatment.

Police are seeking public assistance from anyone who may have witnessed the assault or have information which may help identify those involved in the assault.

The group of four young men are described as being aged between 15 to 18 years old, one was wearing long brown pants and two were wearing knee-length shorts and a hooded jumper.

Police urge anyone with information which may assist with the investigation to contact them on 131 444 or report it anonymously via Crime Stoppers on 131 444 referencing PROMIS number 9075796.